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Bioinformatic Methods II
  • Level Foundation
  • المدة 19 ساعات hours
  • الطبع بواسطة University of Toronto
  • Offered by

عن

Large-scale biology projects such as the sequencing of the human genome and gene expression surveys using RNA-seq, microarrays and other technologies have created a wealth of data for biologists. However, the challenge facing scientists is analyzing and even accessing these data to extract useful information pertaining to the system being studied. This course focuses on employing existing bioinformatic resources " mainly web-based programs and databases " to access the wealth of data to answer questions relevant to the average biologist, and is highly hands-on. Topics covered include multiple sequence alignments, phylogenetics, gene expression data analysis, and protein interaction networks, in two separate parts. The first part, Bioinformatic Methods I, dealt with databases, Blast, multiple sequence alignments, phylogenetics, selection analysis and metagenomics. This, the second part, Bioinformatic Methods II, will cover motif searching, protein-protein interactions, structural bioinformatics, gene expression data analysis, and cis-element predictions. This pair of courses is useful to any student considering graduate school in the biological sciences, as well as students considering molecular medicine. These courses are based on one taught at the University of Toronto to upper-level undergraduates who have some understanding of basic molecular biology. No programming is required for this course although some command line work (though within a web browser) occurs in the 5th module. Bioinformatic Methods II is regularly updated, and was last updated for January 2023.

الوحدات

Protein Motifs

    • 2 Videos
    • 3 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

3 Readings

  • Acknowledgements
  • Course Logistics
  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 1 Quiz

2 Videos

  • Lab Discussion
  • Summary

1 Readings

  • Lab 1 -- Protein Domain, Motif and Profile Analysis

Protein-Protein Interactions

    • 2 Videos
    • 1 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

1 Readings

  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 2 Quiz

2 Videos

  • Lab Discussion
  • Summary

1 Readings

  • Lab 2 -- Protein-Protein Interactions

Protein Structure

    • 2 Videos
    • 1 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

1 Readings

  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 3 Quiz

2 Videos

  • Lab Discussion
  • Summary

1 Readings

  • Lab 3 -- Structural Bioinformatics

Review

    • 1 Assignment
Show info about module content

1 Assignment

  • Quiz: Protein Motifs, Protein-Protein Interactions, and Protein Structure

Gene Expression Analysis I

    • 2 Videos
    • 1 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

1 Readings

  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 4 Quiz

2 Videos

  • Lab Discusssion
  • Summary

1 Readings

  • Lab 4 -- Gene Expression Analysis I

Gene Expression Analysis II

    • 2 Videos
    • 1 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

1 Readings

  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 5 Quiz

2 Videos

  • Lab Discussion
  • Summary

1 Readings

  • Lab 5 -- Gene Expression Data Analysis II

Cis Regulatory Systems

    • 2 Videos
    • 1 Readings
Show info about module content

2 Videos

  • Introduction
  • Lecture

1 Readings

  • Lecture Materials

Lab and Summary

    • 2 Videos
    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Lab 6 Quiz

2 Videos

  • Lab Discussion
  • Summary

1 Readings

  • Lab 6 -- Cis Regulatory Element Mapping and Prediction

Review

    • 1 Readings
    • 2 Assignment
Show info about module content

2 Assignment

  • Quiz: Modules 5-7
  • Final Assignment

1 Readings

  • Final Assignment Instructions

Auto Summary

"Bioinformatic Methods II" focuses on using web-based bioinformatic tools to analyze large-scale biological data. Taught by Coursera, this foundation-level course covers motif searching, protein interactions, structural bioinformatics, and gene expression analysis. Ideal for aspiring grad students in biological sciences and molecular medicine, it spans 1140 minutes and offers Starter, Professional, and Paid subscription options. No programming needed, though basic molecular biology knowledge is recommended.

Nicholas James Provart
Instructor

Nicholas James Provart