- Level Foundation
- المدة 17 ساعات hours
- الطبع بواسطة The Pennsylvania State University
-
Offered by
عن
Not so long ago, it was almost guaranteed that you would die of an infectious disease. In fact, had you been born just 150 years ago, your chances of dying of an infectious disease before you've reached the tender age of 5 would have been extremely high. Since then, science has come a long way in understanding infectious diseases - what they are, how they spread, and how they can be prevented. But diseases like HIV/AIDS, Malaria, Tuberculosis, or the flu are still major killers worldwide, and novel emerging diseases are a constant threat to public health. In addition, the bugs are evolving. Antibiotics, our most potent weapon against bacterial infections, are losing their power because the bacteria are becoming resistant. In this course, we'll explore the major themes of infectious diseases dynamics. After we’ve covered the basics, we'll be looking at the dynamics of the flu, and why we're worried about flu pandemics. We'll be looking at the dynamics of childhood diseases such as measles and whooping cough, which were once considered almost eradicated, but are now making a comeback. We'll explore Malaria, and use it as a case study of the evolution of drug resistance. We'll even be looking at social networks - how diseases can spread from you to your friends to your friends' friends, and so on. And of course we’ll be talking about vaccination too. We’ll also be talking about how mobile phones, social media and crowdsourcing are revolutionizing disease surveillance, giving rise to a new field of digital epidemiology. And yes, we will be talking about Zombies - not human zombies, but zombie ants whose brains are hijacked by an infectious fungus. We're looking forward to having you join us for an exciting course!الوحدات
Course Introduction
3
Readings
- Course Overview
- Course Syllabus
- Glossary of Terms
Pathogens I
4
Videos
- What is an Epidemic?
- Micro and Macro Parasites
- Infection and Disease
- Transmission Types
1
Readings
- Module Overview
Pathogens II
3
Videos
- Reproductive Number
- Epidemic Curve
- Micro-organisms
Review
1
Assignment
- Summative: Pathogens
Hosts I
4
Videos
- Types of Immunity: Innate Immune System
- Types of Immunity: Adaptive Immune System
- Immune Evasion
- Other Determinants of Susceptibility
1
Readings
- Module Overview: Hosts
Hosts II
3
Videos
- Social Influences on Immunity
- Pathogens and Disease
- Detecting an Infectious Disease Outbreak
Review
1
Assignment
- Summative: Hosts
Basics of Ecology I
6
Videos
- Pathogens and Host Extinction
- Force of Infection
- Cycles
- Seasonality
- Flu 1918
- Host Diversity, Host Range
1
Readings
- Module Overview: Basics of Ecology
Basics of Ecology II
3
Videos
- Critical Community Size
- Pathogen-Microbiome Interactions
- The 2014 Ebola Outbreak
Review
1
Assignment
- Summative: Basics of Ecology
Epidemiology I
4
Videos
- Roots of Epidemiology
- Social Networks
- Structure of Networks
- Superspreaders
1
Readings
- Module Overview: Epidemiology
Epidemiology II
4
Videos
- Spatial Hetergeneity
- Movement and Modern Transportation
- Surveillance and Disclosure
- Co-Infection Consequences
Review
1
Assignment
- Summative: Epidemiology
Vaccination I
3
Videos
- Introduction to Control
- Discovery of the First Vaccine
- Global Impact of Vaccination
1
Readings
- Module Overview: Vaccination
Vaccination II
4
Videos
- How Vaccination Works
- Herd Immunity
- Social Networks and Targeted Vaccination
- Vaccination Refusal
Review
1
Assignment
- Summative: Vaccination
Eradication and Elimination
2
Videos
- Eradication and Elimination
- Social Challenges to Eradication
1
Readings
- Module Objectives: Control Mechanisms
Non-pharmaceutical Interventions
3
Videos
- Non-pharmaceutical Interventions: Animals
- Non-pharmaceutical Interventions: Humans 1
- Non-pharmaceutical Interventions: Humans 2
Behavioral Avoidance & Control
4
Videos
- Behavioral Avoidance
- Controlling the Vector
- Consequences of Control
- Vaccination Ethics
Herpesviruses
1
Videos
- New Approaches to an Old Infection
Review
1
Assignment
- Summative: Control Mechanisms
Disease Emergence & Evolution
3
Videos
- Disease Emergence
- Re-emergence
- Evolution General
1
Readings
- Module Overview: Emergence
Drug Resistance
2
Videos
- Antibiotic and Drug Resistance
- Management of Resistance
Impact of Emergence & Evolution of Virulence
2
Videos
- Behavioral And Economic Impact
- Evolution of Virulence
Review
1
Assignment
- Summative: Emergence
Global Health I
4
Videos
- SARS - A Modern Epidemic
- Disease Surveillance - Classical
- Disease Surveillance - Digital
- Culture and Health
1
Readings
- Module Overview: Global Health
Global Health II
5
Videos
- Emerging Disease Issues
- Crop Diseases and Food Security
- Global Pattern of Parasite Biodiversity
- Models of Infectious Diseases
- Zombies
Review
1
Assignment
- Summative: Global Health
Module 1: Pathogens
5
Videos
- Introductions
- What Does It Mean to Be Infectious?
- What is the Impact of Prior Infections on Susceptibility to New Pathogens?
- What Ended the Plague? What Can We Learn About Pandemics?
- Can Behavior Contribute to Susceptibility?
Module 2: Hosts
5
Videos
- Marilyn Roosinck and What’s Different about Plant Epidemiology?
- Can Plants be Vectors of Disease?
- What are Other Determinants of Susceptibility?
- Can Pathogens Change Host Function?
- Immune System Conflict
Module 3: Basics of Ecology
5
Videos
- Eric Harvill and What is the Whole Micro-Biome, Pro-Biotic, Good Bacteria Thing?
- Why Can't Our Antibodies Mutate Like Antigens?
- How Does Microbiome Exchange Therapy Work?
- What are the Best Strategies to Combat Multi-Species Infections?
- How Relevant is the Concept of Critical Community Size?
Module 4: Epidemiology
4
Videos
- Isabella Catadori and the Translation of Her Lab Work into the Field
- Examples of Co-Infections and How They Change Epidemiology of Human Infections
- Super-Shedders v. Super Spreaders and the Pareto Principle
- The Role of Social Media in Epidemiology and how Information is Disseminated
Module 5: Vaccination
4
Videos
- Dr. Vivek Kapur and What Do We Need to Know about Development and Implementation of New Vaccines?
- Why Don't We Have Vaccines for Everything?
- Why Don't We Use Targeted Vaccinations?
- What Are the Benefits of So-Called Gain-of-Function Experiments?
Module 6: Control Mechanisms
4
Videos
- Dr. Moriah Szpara and How/Why do viruses like Varicella and Herpes Re-activate Themselves?
- What are the Challenges to the Eradication of Pathogens and Setting Eradication as a Goal?
- How Does Stress Affect Susceptibility and the Expression of Disease?
- Has there been a Collective Change in Human Behavior in Response to Sexually Transmitted Diseases?
Module 7: Emergence
5
Videos
- What can we do to minimize selection for resistance in vectors?
- Genetic engineering of vectors? pt.1
- Genetic engineering of vectors? pt.2
- What is the role of climate change in disease emergence?
- What can we learn from antibiotic and vaccine use in agriculture?
Module 8: Global Health
4
Videos
- Dr. Craig Cameron and What do We Mean by 'Antivirals?'
- What is it About Polio?
- What About the One Health Concept?
- What is the Next Big Thing?
Auto Summary
Dive into the fascinating world of infectious diseases with the "Epidemics - the Dynamics of Infectious Diseases" course, offered by Coursera. This foundational course is perfect for anyone interested in the Science & Engineering domain, providing a comprehensive understanding of how infectious diseases impact public health. Led by experienced instructors, this course delves into the history and evolution of infectious diseases, examining major killers like HIV/AIDS, Malaria, and Tuberculosis, as well as the persistent threat of the flu. You'll explore the intricacies of disease transmission, the resurgence of childhood diseases like measles and whooping cough, and the pressing issue of antibiotic resistance. With a duration of 1020 minutes, the course covers a wide range of topics, including the dynamics of flu pandemics, the role of social networks in disease spread, and the revolutionary impact of digital epidemiology through mobile phones and social media. You'll even encounter intriguing subjects like the phenomenon of zombie ants controlled by infectious fungi. Choose from flexible subscription options, including Starter and Professional, to best suit your learning needs. Designed for a broad audience, this course is ideal for learners at the foundational level who are eager to understand the complexities of infectious diseases and their prevention. Join us for an engaging and informative journey into the dynamics of epidemics and enhance your knowledge in this critical field.

Dr. Ottar N. Bjornstad

Dr. Rachel A. Smith

Dr. Mary L. Poss

Dr. David P. Hughes

Dr. Peter Hudson

Dr. Matthew Ferrari

Dr. Andrew Read

Dr. Marcel Salathé