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Genome Sequencing (Bioinformatics II)
You may have heard a lot about genome sequencing and its potential to usher in an era of personalized medicine, but what does it mean to sequence a genome? Biologists still cannot read the nucleotides of an entire genome as you would read a book from beginning to end. However, they can read short pieces of DNA. In this course, we will see how graph theory can be used to assemble genomes from these short pieces. We will further learn about brute force algorithms and apply them to sequencing mini-proteins called antibiotics.
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Course by
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Self Paced
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18 ساعات
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الإنجليزية
Case Studies in Personalized Medicine
Learn how advances in biomedicine hold the potential to revolutionize drug development, drug treatments, and disease prevention: where are we now, and what does the future hold? This course will present short primers in genetics and mechanisms underlying variability in drug responses. A series of case studies will be used to illustrate principles of how genetics are being brought to bear on refining diagnoses and on personalizing treatment in rare and common diseases.
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Course by
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Self Paced
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18 ساعات
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الإنجليزية
Algorithms on Strings
World and internet is full of textual information. We search for information using textual queries, we read websites, books, e-mails. All those are strings from the point of view of computer science. To make sense of all that information and make search efficient, search engines use many string algorithms. Moreover, the emerging field of personalized medicine uses many search algorithms to find disease-causing mutations in the human genome. In this online course you will learn key pattern matching concepts: tries, suffix trees, suffix arrays and even the Burrows-Wheeler transform.
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Course by
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Self Paced
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19 ساعات
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الإنجليزية