- Level Professional
- Duration 35 hours
- Course by Universiteit Leiden
-
Offered by
About
Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. What used to be an experimental, risky, and very limited treatment option more than 50 years ago is now routinely performed in many countries worldwide. The number of renal transplants is expected to rise sharply in the next decade since the proportion of patients with end stage renal disease is increasing. Are you interested in clinical kidney, pancreas and islet transplantation? If you are a (bio) medical student or a health care professional who works in the (pre) clinical transplant field this might be the course for you. This course is also for anyone interested in the research and knowledge on clinical transplantation. The course will be taught by a multidisciplinary team of transplant professionals and will give you the state of the art updates. It is divided in 4 modules: 1) Before the transplant 2) The surgical procedures and the challenged patient, including the patient with diabetes 3) Early challenges 4) Late challenges after transplantation. The offered modules will include lectures, interactive patient cases, 3D movies, interviews with well-known experts and with patients and a donor, a serious game to increase knowledge of the field and of course an active forum. Become an expert and join us! The course has been endorsed by The European Society of Organ Transplantation (ESOT), The International Society of Nephrology (ISN) and The Transplantation Society (TTS). This MOOC has been accredited for Continuing Medical Education (CME). Health care professionals who works in the (pre) clinical transplant field, other health care professionals and general practitioners can obtain CME credit at 'LUMC-Boerhaave CME' upon passing the course. For more information we like to refer to the "Additional introduction for obtaining CME credit" module in week 1 of the course For another interesting course on organ donation and transplantation, see Organ Donation: From Death to Life from Cape Town University https://www.coursera.org/learn/organ-donationModules
Introduction to the course
1
Discussions
- Introduce yourself
2
Videos
- Trailer Clinical Kidney Transplantation
- How to succeed in your online class?
1
Readings
- About us: Introduction to the Team
Additional introduction for obtaining CME credit
3
Readings
- CME information
- How to apply for CME credit
- CME FAQs
Introduction
1
Videos
- Short Introduction
Kidney in Health and Disease
2
Videos
- The Kidney in Health and Disease
- Options if Kidneys Fail
Transplant Immunology
1
Discussions
- E-tivity: Which Donor do you choose?
4
Videos
- Immunogenetics
- Introduction to the Immune System
- The Humoral Immune System
- Histocompatibility
Patient Selection
1
Videos
- Cases from Daily Practice - Patient Selection
Review
1
Assignment
- Check your knowledge
Optional
1
Discussions
- The COVID-19 Pandemic and Transplantation
2
Videos
- Eurotransplant Company Film 'More than a Match'
- Interview: Transplant Recipient and Donor: Part 1
Resources
2
Readings
- Glossary
- References
Immunological Testing and Pretransplant Evaluation in more Detail
1
Assignment
- Check your knowledge
1
Peer Review
- Advise your Colleague: a Pretransplantation Question
1
Discussions
- E-tivity: Which Strategy would you choose for this Highly Sensitized Patient?
1
Videos
- Epitopes
2
Readings
- HLA Epitope Matching is the Future
- HLA Antibody Detection: Not All Antibodies are the Same
Introduction
1
Videos
- Short Introduction
The Challenged Patient in Transplantation
4
Videos
- Immunological Challenged Patient: ABO Incompatible Transplants
- Immunological Challenged Patient: Highly Sensitized Patient
- The Diabetic Patient
- The Elderly Patient
Transplant Surgery & Islet Transplantation
3
Videos
- Organ Procurement and Preservation
- Kidney Transplant Surgery
- Simultaneous Pancreas Kidney & Islet Transplantation
Experience a Transplant Procedure in 360 Virtual Reality
1
Peer Review
- Who is Involved in a Transplantation Procedure?
1
Discussions
- E-tivity: Critical Moments During a Donor Nephrectomy
1
Readings
- Introduction to Watching 360 VR Videos
Patient Cases
1
Discussions
- E-tivity: Which treatment do you advise?
2
Videos
- A: Cases from Daily Practice: Different Choices for Different Diabetic Patients
- B: Cases from Daily Practice: Different Choices for Different Diabetic Patients
1
Readings
- Serious Game: A Patient with Immunological Challenges
Review
1
Assignment
- Check your knowledge
Optional
2
Videos
- Interview: Patient with Diabetes
- Interview: Transplant Recipient and Donor: Part 2
Resources
2
Readings
- Glossary
- References
The Procedure and the challenged Patient in more Detail
1
Assignment
- Check your knowledge
1
Discussions
- E-tivity: Do you accept this donor?
2
Videos
- B Cell Replacement and Diabetes Type II
- Surgical Challenged Patients
3
Readings
- Highly Sensitized Patients: The AM Program
- Additional Challenged Transplant Recipients
- Living Kidney Donation
Introduction
1
Videos
- Introduction & Overview of Early Challenges in Transplantation
Early Immune and Non-Immune Related Challenges
4
Videos
- Surgical Challenges in the Early Period
- Ischemia Reperfusion Injury
- Cellular Rejection
- Antibody Mediated Rejection
Immune Suppressive Therapy after Transplantation
1
Discussions
- Advanced e-tivity - MSC therapy in the transplant recipient
2
Videos
- Immune Suppression
- Novel Therapeutics: Cell Therapy after Transplantation
Patient Cases
1
Peer Review
- Design the next game
2
Videos
- Cases from Daily Practice A - Patient Cases with Early Challenges
- Cases from Daily Practice B - Patient Cases with Early Challenges
1
Readings
- Serious Game: Interactive Patient Case
Review
1
Assignment
- Check your knowledge
Optional
2
Discussions
- Etivity: Personalized dosing: what is your advice
- Etivity: What is your therapeutic advice?
1
Videos
- Interview Transplant Recipient & Donor: Part 3
3
Readings
- Optional - Immunesuppressive Regimens and Toxicity Profiles
- Biomarkers
- Therapeutic drug monitoring of immunosuppressive drugs
Resources
2
Readings
- Glossary
- References
Early Challenges after Transplantation in more Detail
1
Assignment
- Check your knowledge
1
Discussions
- Advanced e-tivity - Which cytokine is target of the next drug?
2
Videos
- The Complement System and Transplantation
- Cases from Daily Practice: Patient Case with an Early Challenge
3
Readings
- A closer Look at Antibody Mediated Rejection
- Innate Immunity and Impact on Transplantation
- Molecular Insights into Cellular Rejection
Introduction
1
Videos
- Introduction & Overview of Late Challenges in Transplantation
Over Immune Suppression
1
Discussions
- E-tivity - How can we prevent Pneumocystis Jirovecii Pneumoniae?
3
Videos
- Infections: Overview and CMV infection
- Infections: BK and EBV infection
- Malignancies
1
Readings
- Pneumocystis jirovecii
Metabolic Complications & Challenges after Pancreas, Islet and Kidney Transplantation
1
Discussions
- E-tivity - Why do many transplant patients suffer from obesity?
3
Videos
- Late Challenges after Pancreas and Islet Transplantation
- Post Transplant Diabetes Mellitus
- Cardiovascular Disease
Tolerance
1
Videos
- Tolerance: Interview with Prof. Claas (LUMC) and Prof. Wood (Oxford)
Patient Cases
1
Discussions
- E-tivity - Can the patient himself influence allograft survival
2
Videos
- Cases from Daily Practice A - Patient Cases with Late Challenges
- Cases from Daily Practice B - Patient Cases with Late Challenges
Review
1
Assignment
- Check your knowledge
Optional
3
Assignment
- Patient Case 1: Enhanced Glucose after SPK
- Patient Case 2: Hyperglycemia after Islet Transplantation
- Patient Case 3: A Complication after Pancreas-alone Transplantation
Resources
2
Readings
- Glossary
- References
Late Challenges after Transplantation in more Detail
1
Assignment
- Check your knowledge
1
Peer Review
- Advise your Colleague: Donor Derived Infections
1
Discussions
- E-tivity: How can we reach tolerance?
2
Videos
- Recurrence of Kidney Disease after Transplantation
- Vaccination and Transplantation
2
Readings
- Skin Diseases after Transplantation and Dermatological Aftercare
- Tolerance in more Detail
Final exam
1
Assignment
- Final Exam
Final Honours Exam
1
Assignment
- Final Honours Exam
Auto Summary
Dive into the world of clinical kidney, pancreas, and islet transplantation with this comprehensive course designed for biomedical students, healthcare professionals, and anyone interested in transplantation research. Taught by a team of experts, the course covers pre-transplant procedures, surgical challenges, and post-transplant care through lectures, interactive cases, and engaging multimedia content. Endorsed by major transplantation societies and offering CME credits, this 2100-minute course on Coursera provides professional-level insights with flexible subscription options. Join now to enhance your expertise in this vital medical field.

Marlies Reinders

Frans Claas

Cees van Kooten

Sebastiaan Heidt

Volkert Huurman

Hans de Fijter

Eelco de Koning

Andre Baranski

Ton Rabelink

Aiko de Vries

Jan Nico Bouwes Bavinck

Leo Visser

Ingeborg Bajema