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Advanced Neurobiology I
  • Level Professional
  • Duration 28 hours
  • Course by Peking University
  • Offered by

About

Hello everyone! Welcome to advanced neurobiology! Neuroscience is a wonderful branch of science on how our brain perceives the external world, how our brain thinks, how our brain responds to the outside of the world, and how during disease or aging the neuronal connections deteriorate. We’re trying to understand the molecular, cellular nature and the circuitry arrangement of how nervous system works. Through this course, you'll have a comprehensive understanding of basic neuroanatomy, electral signal transduction, movement and several diseases in the nervous system. This advanced neurobiology course is composed of 2 parts (Advanced neurobiology I and Advanced neurobiology II, and the latter will be online later). They are related to each other on the content but separate on scoring and certification, so you can choose either or both. It’s recommended that you take them sequentially and it’s great if you’ve already acquired a basic understanding of biology. Thank you for joining us!

Modules

Welcome to Advanced Neurobilology!

    • 1 Videos
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1 Videos

  • Welcome to Advanced Neurobilology!

Notice: Slides are available in the first item of every lesson

    • 1 Readings
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1 Readings

  • Slides are available both in video and adneuro@outlook.com

1.1 Anatomy of the Nervous System - Part I

    • 9 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 1.1

9 Videos

  • 1.1.1 Terminology
  • 1.1.2 Central nervous system and blood brain barrier
  • 1.1.3 Meninges
  • 1.1.4 Telencephalon
  • 1.1.5 The localization and globalization theory
  • 1.1.6 White matter
  • 1.1.7 Internal structures
  • 1.1.8 Hippocampus and LTP
  • 1.1.9 Cerebellum

1.2 Anatomy of the Nervous System - Part II

    • 9 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 1.2

9 Videos

  • 1.2.1 Brain stem
  • 1.2.2 Cranial nerves
  • 1.2.3 Ascending and descending tracts and reticular formation
  • 1.2.4 Pons
  • 1.2.5 Reflex and reflex arc
  • 1.2.6 Concepts in the CNS and PNS
  • 1.2.7 Spinal cord
  • 1.2.8 The visceral nervous system
  • 1.2.9 Several pathways of the nervous system

Bonus : Introduction of Neuroscience by Dr. Yi Rao ( In Chinese )

    • 13 Videos
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13 Videos

  • 1 神经科学引言
  • 2 神经科学与人类健康和医药工业
  • 3 神经科学的启蒙时代
  • 4 神经科学的问题、方法、层次
  • 5 脑的功能分区：颅相学与Broca’s area
  • 6 脑的功能分区：皮层的分区
  • 7 脑的功能分区：两半球的差别
  • 8 PET和fMRI
  • 9 外周神经系统
  • 10 神经元学说和神经元极性
  • 11 神经环路
  • 12 神经信息传递：动作电位
  • 13 神经信息传递-化学传递

2 Morphology of the neuronal cell

    • 12 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 2

12 Videos

  • 2.1 Reductionism and hypothesis
  • 2.2 Morphology of the neuron
  • 2.3 Visualization of neurons and the neuron doctrine
  • 2.4 The story of the fluorescent proteins
  • 2.5 Stories of the Nobel prize
  • 2.6 Organic fluorescent probes
  • 2.7 Proteins specifically expressed in neurons and "brainbow" technique
  • 2.8 Microscopy techniques I
  • 2.9 Microscopy techniques II
  • 2.10 The electron microscope
  • 2.11 Glia and myelination
  • 2.12 Research: AIS and Ankyrin G

3.1 Cellular and Molecular Biology of the Neuron - Part I

    • 7 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 3.1

7 Videos

  • 3.1.1 A overview of neurons
  • 3.1.2 Real life situation: Aβ in Alzheimer’s disease
  • 3.1.3 Organelles and cytoskeleton in neurons
  • 3.1.4 Research: induction of the tunneling nanotube
  • 3.1.5 Defects in myelination and related diseases
  • 3.1.6 Synthesis and trafficking of neuronal proteins I
  • 3.1.7 Synthesis and trafficking of neuronal proteins II

3.2 Cellular and Molecular Biology of the Neuron - Part II

    • 9 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 3.2

9 Videos

  • 3.2.1 Cellular information transfer
  • 3.2.2 Signaling molecules
  • 3.2.3 Neurotransmitters and receptors
  • 3.2.4 The synapse
  • 3.2.5 Types of receptors
  • 3.2.6 Crosstalk of cellular signal transduction pathways
  • 3.2.7 The LTP
  • 3.2.8 The molecular mechanism of learning and memory
  • 3.2.9 Glia in a synapse

3.3 Cellular and Molecular Biology of the Neuron - Part III

    • 7 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 3.3

7 Videos

  • 3.3.1 Alzheimer’s disease: introduction and myths
  • 3.3.2 Alzheimer’s disease: pathology
  • 3.3.3 Parkinson’s disease: introduction
  • 3.3.4 Parkinson’s disease: symptoms and prognosis
  • 3.3.5 Parkinson’s disease: pathology
  • 3.3.6 Parkinson’s disease: treatment
  • 3.3.7 Prion diseases

4 Signaling within neurons: electrical properties of neuron and action potentials

    • 7 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 4

7 Videos

  • 4.1 Overview
  • 4.2 The resting potential
  • 4.3 The resting potential and the Nernst equation
  • 4.4 The Nernst Equation
  • 4.5 Biological and electrical proporties of neurons I
  • 4.6 Biological and electrical proporties of neurons II
  • 4.7 Biological and electrical proporties of neurons III.

5 Ion channels and membrane potentials

    • 8 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 5

8 Videos

  • 5.1 Ion channels and membrane potentials I
  • 5.2 Ion channels and membrane potentials II
  • 5.3 Ion channels and membrane potentials III
  • 5.4 Ion channels and membrane potentials IV
  • 5.5 Ion channels and membrane potentials V
  • 5.6 Ion channels and membrane potentials VI
  • 5.7 Ion channels and membrane potentials VII
  • 5.8 Ion channels and membrane potentials VIII

Bonus I : Interview of Dr. Kang Shen

    • 8 Videos
    • 1 Readings
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8 Videos

  • Kang Shen - 1
  • Kang Shen - 2
  • Kang Shen -3
  • Kang Shen - 4
  • Kang Shen - 5
  • Kang Shen - 6
  • Kang Shen - 7
  • Kang Shen - 8

1 Readings

  • Lab page of Dr. Kang Shen

Bonus II : Interview of Dr. Liqun Luo

    • 7 Videos
    • 1 Readings
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7 Videos

  • Liqun Luo - 1
  • Liqun Luo - 2
  • Liqun Luo - 3
  • Liqun Luo - 4
  • Liqun Luo - 5
  • Liqun Luo - 6
  • Liqun Luo - 7

1 Readings

  • Lab page of Dr. Liqun Luo

6 Ion channels, membrane potential and synaptic transmission

    • 8 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 6

8 Videos

  • 6.1 Voltage sensing
  • 6.2 The Na+ gating current
  • 6.3 Inactivation gates
  • 6.4 Ion channel, membrane potential and synaptic transmission I
  • 6.5 Ion channel, membrane potential and synaptic transmission II
  • 6.6 Ion channel, membrane potential and synaptic transmission III
  • 6.7 Ion channel, membrane potential and synaptic transmission IV
  • 6.8 Ion channel, membrane potential and synaptic transmission V

7 Neurotransmitter release

    • 14 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 7

14 Videos

  • 7.1 How does Ca2+ control neurotransmitter release I
  • 7.2 How does Ca2+ control neurotransmitter release II
  • 7.3 How does Ca2+ control neurotransmitter release III
  • 7.4 How does Ca2+ control neurotransmitter release IV
  • 7.5 Molecular mechanism involved in neurotransmetter release I
  • 7.6 Molecular mechanism involved in neurotransmetter release II
  • 7.7 Molecular mechanism involved in neurotransmetter release III
  • 7.8 Molecular mechanism involved in neurotransmetter release IV
  • 7.9 Molecular mechanism involved in neurotransmetter release V
  • 7.10 Molecular mechanism involved in neurotransmetter release VI
  • 7.11 Molecular mechanism involved in neurotransmetter release VII
  • 7.12 Molecular mechanism involved in neurotransmetter release VIII
  • 7.13 Molecular mechanism involved in neurotransmetter release IX
  • 7.14 Molecular mechanism involved in neurotransmetter release X

8 Synaptic transmission

    • 6 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 8

6 Videos

  • 8.1 Synaptic trasmission I
  • 8.2 Synaptic trasmission II
  • 8.3 Synaptic trasmission III
  • 8.4 Synaptic transmission IV
  • 8.5 Synaptic trasmission V
  • 8.6 Synaptic trasmission VI

9 Synapitic plasticity

    • 6 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 9

6 Videos

  • 9.1 Synapitic plasticity I
  • 9.2 Synapitic plasticity II
  • 9.3 Synapitic plasticity III
  • 9.4 Synapitic plasticity IV
  • 9.5 Synapitic plasticity V
  • 9.6 Synapitic plasticity VI

10 Techniques in neuroscience

    • 6 Videos
    • 1 Assignment
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1 Assignment

  • Quiz 10

6 Videos

  • 10.1 Observation and perturbation
  • 10.2 Animal models in neurological research
  • 10.3 Genetic and molecular techniques
  • 10.4 Anatomical techniques
  • 10.5 Mapping synaptic connections
  • 10.6 Patch recording and optical imaging
Yan Zhang
Instructors

Yan Zhang

Yulong Li
Instructors

Yulong Li