- Level Professional
- Duration 26 hours
- Course by Peking University
-
Offered by
About
Hello everyone! Welcome to advanced neurobiology! Neuroscience is a wonderful branch of science on how our brain perceives the external world, how our brain thinks, how our brain responds to the outside of the world, and how during disease or aging the neuronal connections deteriorate. We’re trying to understand the molecular, cellular nature and the circuitry arrangement of how nervous system works. Through this course, you'll have a comprehensive understanding of basic neuroanatomy, electral signal transduction, movement and several diseases in the nervous system. This advanced neurobiology course is composed of 2 parts (Advanced neurobiology I and Advanced neurobiology Il). They are related to each other on the content but not on scoring or certification, so you can choose either or both. It’s recommended that you take them sequentially and it’s great if you’ve already acquired a basic understanding of biology. Thank you for joining us!Modules
Welcome to Advanced Neurobiology!
1
Videos
- Welcome to Advanced Neurobiology!
1
Readings
- Guide to download the slides
1.1 Perception: Vision I
1
Assignment
- Quiz 1.1
10
Videos
- 1.1.1 Ways to sense the environment-I
- 1.1.2 Ways to sense the environment-II
- 1.1.3 Ways to sense the environment-III
- 1.1.4 Sensory transduction-I
- 1.1.5 Sensory transduction-II
- 1.1.6 Sensory processing
- 1.1.7 Sensory representation in the brain
- 1.1.8 Vision
- 1.1.9 Single-photon detection
- 1.1.10 Second messengers
1.2 Perception: Vision II
1
Assignment
- Quiz 1.2
7
Videos
- 1.2.1 Review
- 1.2.2 Phototransduction-I
- 1.2.3 Phototransduction-II
- 1.2.4 Phototransduction-III
- 1.2.5 Color vision-I
- 1.2.6 Color vision-II
- 1.2.7 Signal processing of the retina
2.1 Perception: Auditory I
1
Assignment
- Quiz 2.1
6
Videos
- 2.1.1 Center-Surround Receptive Field
- 2.2.2 The LGN
- 2.2.3 LGN and the visual pathway
- 2.2.4 Simple and complex cells-I
- 2.2.5 Simple and complex cells-II
- 2.2.6 Colors
2.2 Perception: Auditory II
1
Assignment
- Quiz 2.2
8
Videos
- 2.2.1 Sound transduction-I
- 2.2.2 Sound transduction-II
- 2.2.3 Sound transduction-III
- 2.2.4 Sound transduction-IV
- 2.2.5 Sound transduction-V
- 2.2.6 Auditory pathways and the tonotopic map
- 2.2.7 Sound localization-I
- 2.2.8 Sound localization-II
3.1 Chemosensory system: olfaction
1
Assignment
- Quiz 3.1
7
Videos
- 3.1.1 The senses of chemoreception
- 3.1.2 Olfactory organization
- 3.1.3 Olfactory transduction
- 3.1.4 Olfactory adaption
- 3.1.5 Identification of odorant-receptor genes-I
- 3.1.6 Identification of odorant-receptor genes-II
- 3.1.7 Three models of olfactory organization
3.2 Chemosensory system: gustation
1
Assignment
- Quiz 3.2
9
Videos
- 3.2.1 Projection of the olfactory system
- 3.2.2 Circuits in the olfactory bulb-I
- 3.2.3 Circuits in the olfactory bulb-II
- 3.2.4 Taste and taste receptors-I
- 3.2.5 Taste and taste receptors-II
- 3.2.6 Taste and taste receptors-III
- 3.2.7 Taste and taste receptors-IV
- 3.2.8 Taste transduction-I
- 3.2.9 Taste transduction-II
4.1 Touch and pain
1
Assignment
- Quiz 4.1
8
Videos
- 4.1.1 Parallel organization of the somatosensory system-I
- 4.1.2 Parallel organization of the somatosensory system-II
- 4.1.3 Mechanosensory neurons
- 4.1.4 Response properties: adaptation and stimuli & receptive field
- 4.1.5 Mechanotransduction channels-I
- 4.1.6 Mechanotransduction channels-II
- 4.1.7 Somatosensory cortex & somatopic map-I
- 4.1.8 Somatopic map-II, barrel cortex & pain regulation
4.2 Sleep amd arousal (12.7)
1
Assignment
- Quiz 4.2
9
Videos
- 4.2.1 Sleep-I
- 4.2.2 Sleep-II
- 4.2.3 Sleep-III
- 4.2.4 Sleep-IV
- 4.2.5 Circadian and sleep homeostasis
- 4.2.6 Sleep stage-I
- 4.2.7 Sleep stage-II
- 4.2.8 Summary of sleep studies
- 4.2.9 Sleep/waking Flip-flop Model
5.1 Movement and movement disorders: structure and function
1
Assignment
- Quiz 5.1
7
Videos
- 5.1.1 Do you take movement for granted?
- 5.1.2 Brain imaging and functional areas
- 5.1.3 Review of the CNS and PNS and cortical homunculus
- 5.1.4 Review of the cerebellum and basal nuclei
- 5.1.5 Review of the cranial nerves
- 5.1.6 Review of the cranial nerves
- 5.1.7 Spinal cord discomfort
5.2 The two sides of the same coin—function and dysfunction: from molecules to animal
1
Assignment
- Quiz 5.2
9
Videos
- 5.2.1 The ladder-from molecules to animals
- 5.2.2 Biology and disease—why do we biologists care about diseases?
- 5.2.3 Why do we care so much about the 10% genetic forms of neurological diseases?
- 5.2.4 Cellular functions—what are involved in neurological diseases?
- 5.2.5 Recurring features in neurodegeneration
- 5.2.6 Anatomic deficits of AD
- 5.2.7 Cell death in AD
- 5.2.8 Genes involved in AD
- 5.2.9 Practice:what’s the situation in ALS?
Dopaminergic system and basal ganglia function and dysfunctio
1
Assignment
- Quiz 6
9
Videos
- 6.1 The dopamine system
- 6.2 Basal ganglia and its two pathways
- 6.3 HD deficits in basal ganglia
- 6.4 Anatomical deficits of HD
- 6.5 CAG repeats in HD
- 6.6 Are aggregations proper drug targets?
- 6.7 Symptoms of PD
- 6.8 Genes of familial PD
- 6.9 Interventions of PD
Mood and mood disorders
1
Assignment
- Quiz 7
9
Videos
- 7.1 Mood and emotions
- 7.2 Autism
- 7.3 Addiction
- 7.4 Schizophrenia
- 7.5 Depression
- 7.6 Bipolar disorder
- 7.7 Causes of mood disorders
- 7.8 Treatment of depression and bipolar disorder
- 7.9 Attention disorder
Gene and behavior
1
Assignment
- Quiz 8
11
Videos
- 8.1 Introduction of behavior
- 8.2 Bruce effect
- 8.3 Definition of behavior
- 8.4 Classification of behavior
- 8.5 Clock
- 8.6 Transcriptional feed back
- 8.7 Photoentrainment
- 8.8 Gene and sex Ⅰ
- 8.9 Gene and sex Ⅱ
- 8.10 Parabiosis
- 8.11 Leptin
Auto Summary
Explore the intricate workings of the nervous system with "Advanced Neurobiology II" on Coursera. This professional-level course delves into neuroanatomy, electrical signal transduction, movement, and neurological diseases. Ideal for those with a basic biology background, it offers both sequential and standalone learning options. With a duration of 1560 minutes, choose between Starter and Professional subscriptions. Join us to unravel the complexities of the brain under expert guidance.

Chenjian Li

Donggen Luo

Yan Zhang