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Drug Discovery
  • Level Foundation
  • Duration 9 hours
  • Course by University of California San Diego
  • Offered by

About

The University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences Drug Discovery course brings you lectures from both faculty and industry experts. With this course, recorded on campus at UCSD, we seek to share our access to top people in the field who bring an unprecedented range of expertise on drug discovery. In this course you will learn the drug discovery process up to the filing of an Initial New Drug Application or IND. Each week you will learn the steps that a pharmaceutical or biotech company goes through to discover a new therapeutic drug. In this course you will be able to: * Understand the pharmaceutical and biotechnology market a changing landscape * Learn the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates. * Recognize current modern drug discovery based on the lock-and-key theory, which attempts to use one single compound to hit one target to combat the related disease. * Increase understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug. * Define and understand the regulatory responsibilities for drug discovery to file an Investigational New Drug Application (IND). This course is intended as part 1 of a series: Drug Discovery, Drug Development and Drug Commercialization. We would highly recommend that you take the courses in order since it will give you a better understanding on how a drug is discovered in the lab before being tested in clinical trials and then launched in the market place.

Modules

Lesson 1

    • 1 Videos
    • 1 Discussion
Show info about module content

1 Discussions

  • Get to know your fellow Courserians!

1 Videos

  • Welcome!

Pharma & Biotech Industry

    • 4 Videos
    • 1 Readings
    • 1 Discussion
Show info about module content

1 Discussions

  • Mega-mergers: What are their implications?

4 Videos

  • Pharma and Biotechnology Landscape
  • Key Issues for Pharma
  • Global Outlook: What will the Future Look Like?
  • Creating a Sustainable Business

1 Readings

  • Meet the Instructors

Patient-Centric Drug Discovery and Commercialization

    • 1 Videos
Show info about module content

1 Videos

  • Patient-Centric Drug Discovery and Commercialization

Innovation

    • 2 Videos
Show info about module content

2 Videos

  • A New Approach to R&D
  • Innovation and Its Role in Developing Better Drugs

Review

    • 1 Readings
    • 1 Discussion
    • 1 Assignment
Show info about module content

1 Assignment

  • Pharma and Biotech

1 Discussions

  • Pharma and Biotech Changes

1 Readings

  • Lecture Slides

Optional Materials

    • 1 Readings
Show info about module content

1 Readings

  • A new Master Degree in Science in Drug Development & Product Management at UCSD

Drug Discovery: Proteomics, Genomics Part I

    • 3 Videos
Show info about module content

3 Videos

  • Drug Discovery: Proteomics, Genomics I
  • Drug Discovery: Proteomics, Genomics II
  • Drug Discovery: Proteomics, Genomics III

Drug Discovery: Proteomics, Genomics Part II

    • 2 Videos
Show info about module content

2 Videos

  • Drug Discovery: Proteomics, Genomics IV
  • Drug Discovery: Proteomics, Genomics V

Review

    • 1 Readings
    • 1 Discussion
    • 1 Assignment
Show info about module content

1 Assignment

  • Drug Discovery: Proteomics, Genomics

1 Discussions

  • What's the most interesting thing discussed this module?

1 Readings

  • Lecture Slides

Compound Selection & Preclinical Studies Part I

    • 3 Videos
    • 1 Discussion
Show info about module content

1 Discussions

  • Efforts in Drug Discovery: Differences between first-in-class and best-in-class

3 Videos

  • Compound Selection & Preclinical Studies I
  • Compound Selection & Preclinical Studies II
  • Compound Selection & Preclinical Studies III

Compound Selection & Preclinical Studies Part II

    • 3 Videos
    • 1 Discussion
Show info about module content

1 Discussions

  • Develop your own first-in-class drug

3 Videos

  • Compound Selection & Preclinical Studies IV
  • Compound Selection & Preclinical Studies V
  • Compound Selection & Preclinical Studies VI

Review

    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Compound Selection and Pre-clinical Studies

1 Readings

  • Lecture Slides

Challenges in Fragment Based Drug Discovery for Protein Kinases Part I

    • 3 Videos
    • 1 Discussion
Show info about module content

1 Discussions

  • Collaboration among scientific disciplines - how important is it?

3 Videos

  • Challenges in Fragment Based Drug Discovery for Protein Kinases I
  • Challenges in Fragment Based Drug Discovery for Protein Kinases II
  • Challenges in Fragment Based Drug Discovery for Protein Kinases III

Challenges in Fragment Based Drug Discovery for Protein Kinases Part II

    • 2 Videos
    • 1 Readings
    • 1 Discussion
Show info about module content

1 Discussions

  • Clinical Trials Interruptions: What can we learn?

2 Videos

  • Challenges in Fragment Based Drug Discovery for Protein Kinases IV
  • Challenges in Fragment Based Drug Discovery for Protein Kinases V

1 Readings

  • Optional: Examples using structure based approaches

Review

    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Challenges in Fragment Based Drug Discovery for Protein Kinases

1 Readings

  • Lecture Slides

Key Concepts in Drug Delivery Part I

    • 2 Videos
Show info about module content

2 Videos

  • Key Concepts in Drug Delivery I
  • Key Concepts in Drug Delivery II

Key Concepts in Drug Delivery Part II

    • 3 Videos
Show info about module content

3 Videos

  • Key Concepts in Drug Delivery III
  • Key Concepts in Drug Delivery IV
  • Key Concepts in Drug Delivery V

Review

    • 1 Readings
    • 1 Assignment
Show info about module content

1 Assignment

  • Concepts in Drug Delivery Quiz

1 Readings

  • Lecture Slides

How did this course help you?

    • 1 Discussion
Show info about module content

1 Discussions

  • How did this course help you?

Auto Summary

The "Drug Discovery" course by UC San Diego's Skaggs School of Pharmacy on Coursera offers in-depth insights into the pharmaceutical and biotech industries. Led by faculty and industry experts, it covers the entire drug discovery process up to filing an IND application. With a duration of 540 minutes, this foundational course is ideal for learners interested in understanding target selection, compound screening, modern drug discovery theories, and regulatory responsibilities. Subscription options include a starter package, making it accessible for anyone keen on exploring the drug development landscape.

Williams S. Ettouati, Pharm.D.
Instructors

Williams S. Ettouati, Pharm.D.

Joseph D. Ma
Instructors

Joseph D. Ma