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Extracellular Vesicles in Health and Disease
  • Level Professional
  • Duration 12 hours
  • Course by University of California, Irvine
  • Offered by

About

This course aims to provide current understanding about extracellular vesicles (EVs) and their role in health and diseases. The EVs are known to be involved in cell to cell communication. Apart from maintaining normal cell physiology, EVs deliver messages that can drive or influence the progression of a disease. This course discusses recent advances made in the field to give an introduction on their function in health as well as in disease.This course includes four modules. Module 1 is an introduction to the course, and provides an overview of the previous MOOC on EVs “Basics of Extracellular Vesicles”. Module 2 focuses on the role of EVs in physiological conditions and gives various examples on their role in metabolism, inflammation, immunity and pregnancy and coagulation. This module also briefly covers the topic of microorganism-derived EVs such as vesicles from bacteria and discusses EVs from apoptotic and senescent cells. In Module 3, we focus on the role of EVs in cancer: how EVs can mediate communication between the tumour and its microenvironment, the functional role of immune cell-derived EVs in development of cancer, as well as the role of EVs in cancer cell proliferation, survival, metastasis and drug resistance. In Module 4, the role of EVs in diseases of the cardiovascular, haematopoietic, nervous, respiratory and urinary systems, and infectious diseases will be presented.This course is recommended for intermediate learners or anyone who is interested in the field of extracellular vesicles and their role in a particular disease including scientists, clinicians, or cell and molecular biologists who look to broaden their understanding of the field.

Modules

Introduction and Review of MOOC I

    • 2 Videos
    • 1 Readings
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2 Videos

  • Lecture 1.1: Introduction to MOOC II
  • Lecture 1.2: Overview of MOOC I

1 Readings

  • Start Here

Lectures

    • 7 Videos
    • 1 Assignment
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1 Assignment

  • Module 2

7 Videos

  • Lecture 2.1— Bacterial Extracellular Vesicles (crosstalk with the microbiome)
  • Lecture 2.2 — Coagulation
  • Lecture 2.3 — Immunity
  • Lecture 2.4 — Metabolism
  • Lecture 2.5 — Pregnancy
  • Lecture 2.6 — Inflammation and Stress Responses
  • Lecture 2.7 — Apoptotic & Senescence Physiological Processes

Lectures

    • 5 Videos
    • 1 Assignment
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1 Assignment

  • Module 3

5 Videos

  • Lecture 3.1 — Oncology: Shared Functional Aspects of EVs in Oncology
  • Lecture 3.2 — Oncology: Communication with Tumour Microenvironment
  • Lecture 3.3 — Oncology: Tumour and Immune System Interaction
  • Lecture 3.4 — Oncology: Cancer Proliferation and Survival
  • Lecture 3.5 — Oncology: Cancer Biomarker

Lectures

    • 7 Videos
    • 1 Assignment
Show info about module content

1 Assignment

  • Module 4

7 Videos

  • Lecture 4.1— Cardiovascular Diseases
  • Lecture 4.2 — Haematological Diseases I
  • Lecture 4.3 — Haematological Diseases II
  • Lecture 4.4 — Diseases of the Nervous System
  • Lecture 4.5 — Infectious Diseases
  • Lecture 4.6 — Urology
  • Lecture 4.7 — Respiratory Diseases

Auto Summary

Explore the intricate world of extracellular vesicles (EVs) with the engaging course "Extracellular Vesicles in Health and Disease." Offered within the Science & Engineering domain and presented by Coursera, this professional-level course delves into the crucial role EVs play in cell communication and disease progression. Over four comprehensive modules, learners will uncover the functions of EVs in both healthy physiology and various diseases, including cancer, cardiovascular, haematopoietic, nervous, respiratory, and urinary system diseases, as well as infections. Module 1 introduces the foundational concepts, while Module 2 explores EVs' roles in metabolism, inflammation, immunity, pregnancy, and coagulation, even touching on microorganism-derived vesicles. Module 3 is dedicated to understanding EVs in cancer development, examining their impact on tumor microenvironments, immune responses, and drug resistance. Module 4 broadens the scope to include EVs' involvement in a range of systemic diseases. This course is tailored for intermediate learners and professionals—scientists, clinicians, cell, and molecular biologists—seeking to deepen their knowledge of EVs. With a duration of 720 minutes, participants can choose from Starter or Professional subscription options to suit their learning needs. Embark on this educational journey to enhance your expertise in this fascinating and evolving field.

Dr Carolina Soekmadji
Instructor

Dr Carolina Soekmadji