- Level Professional
- Duration 8 hours
- Course by Imperial College London
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Offered by
About
In this course, you will learn about the role of immune responses of the adaptive (acquired) immune system which provides specialised immunity against pathogens. Guided by our researchers in the Department of Immunity and Inflammation, we will take a closer look at the lymphocyte subsets and mechanisms involved in this delayed finely tuned response occurring days to weeks after the initial exposure to microbial antigens. We will also focus on the versatile cellular components which can distinguish between self- and nonself antigens and on how age affects the immune responses.Modules
Course introduction
3
Videos
- Introduction
- The innate and adaptive immune systems working together
- The adaptive responses
1
Readings
- Welcome
B cell effector functions and tolerance
2
Assignment
- Week 1 Practice Quiz
- B cell effector functions and tolerance
4
Videos
- The response strategies of adaptive immunity
- B cell effector functions - Part 1
- B cell effector functions - Part 2
- B cell tolerance
3
Readings
- B cells, antigens and antibodies
- B cell development and lineage commitment
- B cell responses to antigens
T cell activation, T helper subsets and receptors
3
Assignment
- Week 2 Practice Quiz 1
- Week 2 Practice Quiz 2
- T cell activation, T helper subsets and receptors
2
Videos
- T helper cells subsets - Th1, Th2 and beyond
- The thymus and T cell repertoire selection
2
Readings
- T cell activation, T helper subsets and receptors
- T helper cell subsets and their functions
Cytotoxic killing
2
Assignment
- Week 1 Practice Quiz
- Cytotoxic killing
1
Videos
- Cytotoxic killing
2
Readings
- Cytotoxic killing
- More on cytotoxic killing
Regulatory T cells
2
Assignment
- Week 4 Practice Quiz
- Regulatory T cells
1
Videos
- Regulatory T cell biology
2
Readings
- Regulatory T cells
- Treg functions
Lymphocyte recirculation and homing
2
Assignment
- Week 5 Practice Quiz
- Lymphocyte recirculation and homing
2
Videos
- Lymphocyte recirculation
- Lymphocyte homing to tissues
2
Readings
- Lymphocyte recirculation and homing
- Diapedesis
The effect of age on the function of the immune system
2
Assignment
- Week 6 Practice Quiz
- The effect of age on the function of the immune system
1
Videos
- Ageing of the immune system
2
Readings
- The effect of age on the function of the immune system
- Inflammaging
Auto Summary
Discover the intricacies of the adaptive immune system with Coursera's "Immunology: Adaptive Immune System" course. Tailored for professionals in Science & Engineering, this 480-minute course delves into lymphocyte subsets, self- and nonself antigen recognition, and the impact of aging on immunity. Led by experts from the Department of Immunity and Inflammation, you'll gain specialized knowledge on the adaptive immune response. Available through a Starter subscription, this course is perfect for those seeking to deepen their understanding of immunological processes.

Malgorzata (Maggie) Trela

Sophie Rutschmann