- Level Professional
- Duration 6 hours
- Course by Imperial College London
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Offered by
About
Our immune system is a powerful network. It protects us from external threats, such as harmful substances and pathogenic agents, as well as cellular changes which could lead to diseases. Complications emerge when our natural defences do not function properly, which can result in immune disorders. These can take the form of less severe issues such as insect allergy. Others are more harmful, such as auto aggressive immune reactions, that lead to localised or systemic tissue damage. In this course, you will learn about immune system failures which can cause insufficient responses to internal or external threats. We will look at immune deficiencies. These weaken an individual’s immunity and leave them unable to effectively fight infections or manage disease. We will examine the consequences of chronic inflammation on the immune system, in the context of ectopic lymphoid organs. We will also examine immune system malfunctions in tumour development, and the role of viral infections in human cancer.Modules
Course introduction
2
Videos
- Introduction
- Immune response regulation and disorders
1
Readings
- Course introduction
Immunodeficiencies
2
Assignment
- Week 1 Practice Quiz
- Immunodeficiencies
2
Videos
- Primary and secondary immunodeficiencies
- Human immune deficiencies
5
Readings
- Immunodeficiencies introduction
- Primary immunodeficiencies
- ‘The boy in the bubble’
- Secondary immunodeficiencies
- Acquired immunodeficiency syndrome (AIDS)
Tertiary lymphoid structures
2
Assignment
- Week 2 Practice Quiz
- Tertiary lymphoid structures
1
Videos
- Tertiary lymphoid structures
3
Readings
- Introduction
- TLS and inflammation
- TLS and their potential in immunotherapy
Tumour immunology
2
Assignment
- Week 3 Practice Quiz
- Tumour immunology
3
Videos
- Tumour cells, cancer and immune mechanisms
- Introduction to tumour immunology – Part 1
- Introduction to tumour immunology – Part 2
2
Readings
- Introduction
- Human endogenous retroviruses (HERVs) and cancer
Viral persistence and human cancer
2
Assignment
- Week 4 Practice Quiz
- Viral persistence and human cancer
2
Videos
- Virus persistence and human cancer – Part 1
- Virus persistence and human cancer – Part 2
2
Readings
- Introduction
- Oncolytic viruses in anti-cancer treatment
Auto Summary
Explore the complexities of the immune system in "Immunology: Immune Failures and Cancer Immunology," a professional-level course in the Science & Engineering domain. Guided by expert instructors on Coursera, delve into immune deficiencies, chronic inflammation, and their roles in tumour development and cancer. With a duration of 360 minutes, flexible subscription options include Starter and Professional plans. Ideal for science professionals eager to deepen their understanding of immune system malfunctions in disease contexts.

Malgorzata (Maggie) Trela

Sophie Rutschmann